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FeCl 3 : Highly Efficient Catalyst for Synthesis of α ‐Amino Nitriles
Author(s) -
Heravi Majid M.,
Ebrahimzadeh Mojgan,
Oskooie Hossein A.,
Baghernejad Bita
Publication year - 2010
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201090100
Subject(s) - chemistry , trimethylsilyl cyanide , catalysis , filtration (mathematics) , solid acid , solvent , organic chemistry , cyanide , coupling reaction , combinatorial chemistry , polymer chemistry , statistics , mathematics
Abstract α ‐Amino nitriles are synthesized by the three‐component coupling reaction of aldehydes, amines and trimethylsilyl cyanide using FeCl 3 as a solid acid catalyst, under solvent‐free conditions in good yields. The catalyst was recovered by simple filtration and was recycled in subsequent reactions.