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Highly Efficient and Regio‐selective Glucosylation of 25( S ) Ruscogenin by Gliocladium deliquescens NRRL1086
Author(s) -
Chen Naidong,
Zhang Jian,
Liu Jihua,
Yu Boyang
Publication year - 2010
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201090093
Subject(s) - chemistry , yield (engineering) , transformation (genetics) , glycoside , stereochemistry , biochemistry , materials science , metallurgy , gene
A new steroidal glycoside, 25( S ) ruscogenin 1‐ O ‐ β ‐ D ‐glucopyranoside ( 2 ) was obtained through the microbial transformation of 25( S ) ruscogenin ( 1 ) by G . deliquescens NRRL1086 in 54% isolated yield. The structure of the product was elucidated by IR, MS and NMR spectra. This is the first report on the preparation of steroidal saponins by microbial transformation.