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KHSO 4 as an Efficient Catalytic System for the Regiospecific Nitration of Phenols with Metal Nitrates
Author(s) -
Baghernejad Bita,
Oskooie Hossein A.,
Heravi Majid M.,
Beheshtiha Yahia Sh.
Publication year - 2010
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201090085
Subject(s) - chemistry , nitration , phenols , selectivity , catalysis , acetonitrile , phenol , metal , nitrate , organic chemistry , inorganic chemistry
Highly regiospecific mononitration of phenol and substituted phenols was accomplished employing a metal nitrate and a catalytic amount of KHSO 4 in acetonitrile. An exclusive ortho ‐selectivity was observed with excellent yields. A variety of metal nitrates were used to obtain o ‐nitrophenols exclusively in good to excellent yields. The use of KHSO 4 is key for the selectivity observed.