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Synthesis and Antifungal Bioactivity of Methyl 2‐Methoxyimino‐ 2‐{2‐[(substituted benzylidene)aminooxymethyl]phenyl}acetate and 2‐Methoxyimino‐2‐{2‐[(substituted benzylidene)aminooxy‐ methyl]phenyl}‐ N ‐methylacetamide Derivatives
Author(s) -
Li Guohua,
Yang Hong
Publication year - 2009
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.200990345
Subject(s) - chemistry , pyricularia , botrytis cinerea , gibberella zeae , stereochemistry , antifungal , rhizoctonia solani , botrytis , microbiology and biotechnology , botany , fusarium , biology
Ten methyl 2‐methoxyimino‐2‐{2‐[(substituted benzylidene)aminooxymethyl]phenyl}acetate and 2‐methoxy‐ imino‐2‐{2‐[(substituted benzylidene)aminooxymethyl]phenyl}‐ N ‐methylacetamide derivatives were synthesized. Structures of the new compounds were characterized by IR, 1 H NMR and GC‐MS data. These compounds at 10 µg/mL were tested in vitro against five pathogenic fungi, namely, Sclerotonia, Botrytis cinerea Pers, Gibberella zeae , Rhizoctorua solani and Pyricularia oryzae . Compounds G 5 , G 6 , G 7 and G 8 showed potent antifungal activities against Botrytis cinerea Pers , G 7 against Gibberella zeae and G 7 , G 8 against Rhizoctorua solani , respectively.