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One‐pot Synthesis of 1,8‐Dioxo‐decahydroacridine Derivatives in Aqueous Media
Author(s) -
Balalaie Saeed,
Chadegani Fatemeh,
Darviche Fatemeh,
Bijanzadeh Hamid Reza
Publication year - 2009
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.200990328
Subject(s) - chemistry , dimedone , ammonium acetate , ammonium chloride , aqueous medium , aqueous solution , ammonium , one pot synthesis , chloride , organic chemistry , aryl , medicinal chemistry , nuclear chemistry , catalysis , high performance liquid chromatography , alkyl
Abstract A new and efficient method for the synthesis of 1,8‐dioxo‐9‐aryl‐decahydroacridine derivatives was developed via a one‐pot three component reaction of dimedone, aromatic aldehydes and ammonium acetate in the presence of ammonium chloride, or Zn(OAc) 2 ·2H 2 O or L ‐proline separately in water in the short period of time and high yields.