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Microwave‐assisted Synthesis of Pyrazolo[4,3‐ f ]quinolin‐7‐one Derivatives via Multi‐component Reactions
Author(s) -
Peng Juhua,
Hao Wenjuan,
Wang Xiang,
Tu Shujiang,
Ma Ning,
Zhang Ge
Publication year - 2009
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.200990287
Subject(s) - chemistry , component (thermodynamics) , microwave , combinatorial chemistry , computational chemistry , organic chemistry , thermodynamics , quantum mechanics , physics
A series of new pyrazolo[4,3‐ f ]quinolin‐7‐one derivatives were synthesized by multi‐component reactions of equimolar amount of aromatic aldehydes with 2,2‐dimethyl‐1,3‐dioxane‐4,6‐dione and 1 H ‐indazol‐5‐amine in ethylene glycol without catalyst under microwave irradiation. This one‐pot protocol has the advantage of good yields, simple workup procedure and shorter reaction time.