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Cross‐aldol Condensation of Cycloalkanones and Aromatic Aldehydes in the Presence of Nanoporous Silica‐based Sulfonic Acid (SiO 2 ‐Pr‐SO 3 H) under Solvent Free Conditions
Author(s) -
MOHAMMADI ZIARANI Ghodsi,
BADIEI Alireza,
ABBASI Alireza,
FARAHANI Zahra
Publication year - 2009
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.200990259
Subject(s) - chemistry , nanoporous , aldol condensation , sulfonic acid , solid acid , catalysis , condensation , reactivity (psychology) , solvent , organic chemistry , condensation reaction , aldol reaction , filtration (mathematics) , medicine , physics , alternative medicine , pathology , thermodynamics , statistics , mathematics
The aromatic aldehydes underwent cross aldol condensation with cycloalkanones in the presence of a catalytic amount of nanoporous silica‐based sulfonic acid (SiO 2 ‐Pr‐SO 3 H) under solvent‐free conditions to afford the corresponding α , α′ ‐bis(substituted benzylidene)cycloalkanones in excellent yields with short reaction time without any side reactions. This method is very general, simple and environmentally friendly in contrast with other existing methods. SiO 2 ‐Pr‐SO 3 H was proved to be an efficient heterogeneous solid acid catalyst, which could be easily handled and removed from the reaction mixture by simple filtration, and also recovered and reused without loss of reactivity.