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Synthesis and Biological Activity of 4,5‐Dihydro‐1,2,4‐triazole‐5‐thione Schiff Base
Author(s) -
SUN Xiaohong,
BAI Yan,
LIU Yuanfa,
CHEN Bang,
JIA Yingqi,
ZENG Zhenfang
Publication year - 2009
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.200990234
Subject(s) - chemistry , schiff base , 1,2,4 triazole , triazole , elemental analysis , base (topology) , proton nmr , carbon 13 nmr , fungicide , combinatorial chemistry , organic chemistry , medicinal chemistry , stereochemistry , botany , mathematical analysis , mathematics , biology
The 4,5‐dihydro‐1,2,4‐triazole Schiff base derivatives were synthesized with 4‐amino‐4,5‐dihydro‐3‐(phenoxy‐ methyl)‐1 H ‐1,2,4‐triazole‐5‐thione and substituted benzaldehydes. The chemical structures of the compounds have been confirmed by 1 H NMR, IR spectra and elemental analysis. Their biological activities were investigated, and the results showed that they exhibited good fungicidal activities.