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Pd/C/PPh 3 : A Simple and Efficient Catalyst System for Double Carbonylation Reactions
Author(s) -
LIU Jianming,
ZHENG Shuzhan,
SUN Wei,
XIA Chungu
Publication year - 2009
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.200990101
Subject(s) - chemistry , diethylamine , carbonylation , iodobenzene , catalysis , carbon monoxide , amide , selectivity , aryl , organic chemistry , palladium , combinatorial chemistry , alkyl
The double carbonylation of iodobenzene and diethylamine proceeds smoothly in the presence of Pd/C and carbon monoxide to afford the corresponding α ‐keto amide in good yields with excellent selectivity. In addition, other aryl iodides and secondary amines also react under similar conditions to form α ‐keto amides in good yields.