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Aza‐Michael Addition of Isatin and Phthalimide to Symmetrical Fumaric Esters in Ionic Liquid Media
Author(s) -
IMANZADEH Gholam Hassan,
MOLLAEI TAVANA Mahdieh,
ZAMANLOO Mohammad Reza,
MANSOORI Yagoub
Publication year - 2009
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.200990064
Subject(s) - chemistry , isatin , phthalimide , michael reaction , ionic liquid , alkoxy group , fumaric acid , adduct , organic chemistry , ionic bonding , steric effects , polymer chemistry , medicinal chemistry , ion , alkyl , catalysis
Highly efficient aza‐Michael additions of isatin and phthalimide to symmetrical fumaric esters in ionic liquid media to produce the corresponding Michael adducts in excellent yields are described which were performed at 100 °C for 1–5 h. The results show that these aza‐Michael additions are not effective with fumaric esters containing sterically hindered alkoxy groups.