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Heterogeneous Palladium Chloride Catalyzed Ligand‐free Suzuki‐Miyaura Coupling Reactions at Ambient Temperature
Author(s) -
WANG Min,
WANG Lei
Publication year - 2008
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.200890304
Subject(s) - chemistry , sodium tetraphenylborate , phenylboronic acid , catalysis , palladium , ligand (biochemistry) , coupling reaction , chloride , suzuki reaction , inorganic chemistry , organic chemistry , ion , biochemistry , receptor
Abstract A mild and efficient ligand‐free Suzuki‐Miyaura coupling reaction catalyzed by heterogeneous palladium chloride was developed at room temperature in a short reaction time under air atmosphere. Various phenyl iodides, bromides and activated chlorides were coupled with sodium tetraphenylborate or phenylboronic acids efficiently to afford the corresponding cross‐coupled products in good to excellent yields. Furthermore, the catalyst could be recycled up to four times without loss of its activity.