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Oxalic Acid Catalyzed Three Component One Pot Synthesis of 3,4‐Dihydroquinazolin‐4‐ones
Author(s) -
SANGSHETTI JaiprakashN.,
KOKARE NagnnathD.,
SHINDE DevanandB.
Publication year - 2008
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.200890272
Subject(s) - chemistry , oxalic acid , triethyl orthoformate , catalysis , combinatorial chemistry , component (thermodynamics) , organic chemistry , physics , thermodynamics
An efficient one‐pot method for synthesis of an array of 3,4‐dihydroquinazolin‐4‐ones from anthranilicacid, triethyl orthoformate, and anilines using oxalic acid as a catalyst was described. The present protocol offers improvements for the synthesis of 3,4‐dihydroquinazolin‐4‐ones with regard to short reaction time, high yields of products, and simplicity in operation.