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Synthesis, Structure and Biological Activities of Some Novel N ‐(4,6‐Disubstituted‐pyrimidin‐2‐yl)‐ N′ ‐(trifluoromethylphenyl)‐guanidine Derivatives
Author(s) -
HE FengQi,
LIU XingHai,
WANG BaoLei,
LI YongHong,
LI ZhengMing
Publication year - 2008
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.200890268
Subject(s) - chemistry , guanidine , brassica , fourier transform infrared spectroscopy , proton nmr , nuclear chemistry , crystal structure , stereochemistry , medicinal chemistry , organic chemistry , chemical engineering , botany , engineering , biology
A novel series of guanidine derivatives were designed, synthesized and confirmed by FTIR, MS, 1 H NMR and elemental analysis. The single crystal structure of 11b was determined by X‐ray diffraction. Herbicidal activities of these guanidine derivatives were evaluated through barnyardgrass and rape cup tests, among which compounds 11a , 11b , and 11c against Brassica campestris reached 71.2%, 86.7%, and 86.9% at 100 µg·mL −1 respectively. The preliminary ketol‐acid reductoisomerase test showed that the synthesized compounds had weak activities.