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Anhydrous K 2 CO 3 ‐mediated Tandem Deprotection of (Un)substituted Phenyl Methanesulfonate/S N Ar Reactions to Construct Unsymmetrical Diphenyl Ethers in an Ionic Liquid
Author(s) -
XU Hui,
YE Fei,
DAI HuiLing
Publication year - 2008
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.200890266
Subject(s) - chemistry , anhydrous , ionic liquid , tandem , tetrafluoroborate , halide , solvent , medicinal chemistry , nucleophilic substitution , cascade reaction , nucleophile , organic chemistry , catalysis , materials science , composite material
In an ionic liquid [Bmim]BF 4 (1‐butyl‐3‐methylimidazolium tetrafluoroborate), an efficient anhydrous K 2 CO 3 ‐mediated tandem deprotection of (un)substituted phenyl methanesulfonates and nucleophilic aromatic substitution reactions (S N Ar) with activated (un)substituted phenyl halides to synthesize unsymmetrical diphenyl ethers has been described. The solvent could be recycled without loss of any efficiency, and the procedure was quite convenient, practical and environmentally benign.