Premium
Synthesis of β ‐Amino Acids via Catalyst‐ and Solvent‐Free Aza‐Michael Reaction
Author(s) -
ZOU Bo,
JIANG HuanFeng
Publication year - 2008
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.200890238
Subject(s) - chemistry , michael reaction , catalysis , environmentally friendly , organic chemistry , amino acid , solvent , combinatorial chemistry , biochemistry , ecology , biology
A safe, environmentally friendly and cost‐effective method for the synthesis of β ‐amino acid derivatives has been developed. Treatment of α , β ‐unsaturated compounds with aliphatic amines furnishes β ‐amino acid derivatives in good to excellent yields via a catalyst‐ and solvent‐free aza‐Michael addition.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom