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Uracil Grafted Carbon Electrode:Electrocatalytic Behavior of Tryptophan, Tyrosine, Catecholamine and Related Compounds
Author(s) -
LIN XiangQin,
KANG GuangFeng,
ZHU XiaoHong
Publication year - 2008
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.200890129
Subject(s) - chemistry , differential pulse voltammetry , ascorbic acid , detection limit , uracil , electrochemistry , tryptophan , cyclic voltammetry , glassy carbon , x ray photoelectron spectroscopy , electrode , uric acid , inorganic chemistry , nuclear chemistry , chromatography , chemical engineering , biochemistry , amino acid , dna , food science , engineering
A uracil grafted glassy carbon electrode (Ura/GCE) was fabricated and characterized by X‐ray photoelectron spectroscopy (XPS), cyclic voltammertry (CV) and differential pulse voltammetry (DPV) techniques. The electrochemical behavior of tryptophan (Trp), tyrosine (Tyr), catecholamine such as dopamine (DA), epinephrine (EP) and norepinephrine (NE), and related compounds involving uric acid (UA) and ascorbic acid (AA) at the Ura/GCE was investigated. All these bioactive species could be electrocatalytically oxidized to generate very different current sensitivities. This electrode can be used as a versatile electrochemical sensor for DA, EP, NE, UA, Trp and Tyr determination. The DPV peak potential, current sensitivity, linear range and detection limit of these species were obtained and used for analysis of molecular interactions between uracil and those electroactive species. A mechanism for the surface accumulation was discussed.