Premium
Preparation and Evaluation of a Novel Cellulose Tris(N‐3,5‐dimethylphenylcarbamate) Chiral Stationary Phase
Author(s) -
GE Jin,
ZHAO Liang,
SHI YanPing
Publication year - 2008
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.200890008
Subject(s) - chemistry , tris , acetonitrile , cellulose , coating , phase (matter) , chiral column chromatography , repeatability , chromatography , chemical engineering , organic chemistry , nuclear chemistry , biochemistry , engineering
A novel cellulose tris( N ‐3,5‐dimethylphenylcarbamate) (CDMPC) chiral stationary phase (CSP) was prepared by coating CDMPC on TiO 2 /SiO 2 , which was prepared by coating titania nanoparticles on silica through a self‐assemble technique. At first, 2‐hydroxyl‐phenyl acetonitrile and α ‐phenylethanol were separated on this new CSP to evaluate the chiral separation ability. Then, two pesticides, matalaxyl and diclofop‐methyl were separated. The influence of the mobile phase composition on the enantioselectivity was discussed, and the repeatability and stability of the CSP were studied too.