A Novel Stereoselective Synthesis of (1 Z ,3 E )‐2‐Phenyl(or  p ‐Tolyl)sulfonyl‐substituted 1,3‐Dienes via Palladium Catalyzed Cross‐coupling Reactions of ( E )‐ α ‐Iodovinyl Sulfones | Zendy

HU RongHua | Zendy; CHEN GuiQin | Zendy; CAI MingZhong | Zendy

Premium

A Novel Stereoselective Synthesis of (1 Z ,3 E )‐2‐Phenyl(or p ‐Tolyl)sulfonyl‐substituted 1,3‐Dienes via Palladium Catalyzed Cross‐coupling Reactions of ( E )‐ α ‐Iodovinyl Sulfones

Author(s) -

HU RongHua,

CHEN GuiQin,

CAI MingZhong

Publication year - 2007

Publication title -

chinese journal of chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.28

H-Index - 41

eISSN - 1614-7065

pISSN - 1001-604X

DOI - 10.1002/cjoc.200790355

Subject(s) - chemistry , stereoselectivity , sulfonyl , catalysis , palladium , sulfone , medicinal chemistry , coupling reaction , stereochemistry , organic chemistry , alkyl

( E )‐ α ‐Stannylvinyl phenyl(or p ‐tolyl)sulfones underwent an iododestannylation reaction to afford ( E )‐ α ‐iodovinyl phenyl(or p ‐tolyl)sulfones 1 , which reacted with ( E )‐alkenylzirconium(IV) complexes 2 produced in situ by hydrozirconation of terminal alkynes in the presence of a Pd(PPh 3 ) 4 catalyst to afford stereoselectively (1 Z ,3 E )‐2‐ phenyl(or p ‐tolyl)sulfonyl‐substituted 1,3‐dienes 3 in good yields.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research