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One‐Pot Synthesis of 1,2,3‐Triazoles using Polymer‐Supported Propyne in Aqueous Solution
Author(s) -
Shang YongJia,
Ren LianBing,
Wang DongMei
Publication year - 2007
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.200790224
Subject(s) - chemistry , sonogashira coupling , aqueous solution , ethylene glycol , cycloaddition , propyne , combinatorial chemistry , component (thermodynamics) , 1,3 dipolar cycloaddition , organic chemistry , catalysis , palladium , physics , thermodynamics
A practical and efficient liquid‐phase synthesis of 1,2,3‐triazoles using poly(ethylene glycol) as support in aqueous solution was described. The title compounds, 1,2,3‐triazoles 5 were obtained by a one‐pot three‐component 1,3‐dipolar cycloaddition reaction in middle yields. In addition, a series of unexpected products 7 of Sonogashira reaction were also formed under the same condition.