Premium
Accelerated Hydrolysis of p ‐Nitrophenyl Picolinate Catalyzed by Metallomicelle Made from a Novel Macrocyclic Polyamine Copper(II) Complex
Author(s) -
Kou XingMing,
Zhao GuoPo,
Huang Zhong,
Tian YuHua,
Meng XiangGuang,
Zeng XianCheng
Publication year - 2007
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.200790142
Subject(s) - chemistry , ligand (biochemistry) , polyamine , deprotonation , hydrolysis , catalysis , copper , polymer chemistry , medicinal chemistry , macrocyclic ligand , substrate (aquarium) , metal , combinatorial chemistry , stereochemistry , organic chemistry , ion , biochemistry , oceanography , receptor , geology
A copper(II) complex 1 of a novel macrocyclic polyamine ligand with hydroxylethyl pendant groups, 4,11‐bis(hydroxylethyl)‐5,7,7,12,14,14‐hexamethyl‐1,4,8,11‐tetraazacyclotetradecane ( L ) has been synthesized and characterized. Rate enhancement for hydrolysis of p ‐nitrophenyl picolinate (PNPP) catalyzed by 1 was studied kinetically under Brij35 micellar condition. For comparision, the catalytic activity of corresponding copper(II) complex 2 of non‐substituted macrocyclic polyamine ligand, 5,7,7,12,14,14‐hexamethyl‐1,4,8,11‐tetraaza‐cyclote‐ tradecane ( L′ ) toward the hydrolysis of PNPP was also investigated. The results indicate that the macrocyclic polyamine copper(II) complex 1 effectively catalyzed the hydrolysis of PNPP, and the pendant ligand hydroxyl group or deprotonated pendant ligand hydroxyl group can act as catalytically active species in the reaction. A ternary complex kinetic model involving metal ion, ligand and substrate has been proposed, and the results confirmed the reasonability of such kinetic model.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom