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Novel Stereoselective Synthesis of ( E )‐ β ‐Silylvinylstannanes via Hydromagnesiation of Silylarylacetylenes
Author(s) -
Huang Bin,
Zhou Zhou,
Cai MingZhong
Publication year - 2006
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.200690277
Subject(s) - chemistry , stereoselectivity , diethyl ether , reagent , grignard reagent , grignard reaction , organic chemistry , ether , medicinal chemistry , combinatorial chemistry , catalysis
Hydromagnesiation of silylarylacetylenes 1 in diethyl ether gave ( E )‐ β ‐silylvinyl Grignard reagents 2 , which reacted with trialkylstannyl chlorides 3 to afford stereoselectively ( E )‐ β ‐silylvinylstannanes 4 in good yields.