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Effect of Enteral Nutrition Formula on Fat Absorption and Serum Free Fatty Acid Profiles in Rat with Short‐Bowel Syndrome
Author(s) -
Zhou Jiang,
Tan Li,
Wang XueHao,
Ju HuangXian
Publication year - 2006
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.200690255
Subject(s) - short bowel syndrome , chemistry , parenteral nutrition , medicine , enteral administration , fatty acid , absorption (acoustics) , molar absorptivity , arginine , endocrinology , biochemistry , amino acid , physics , acoustics , optics
Abstract The effects of enteral nutrition containing long chain triglycerides (LCT) and medium chain triglycerides (MCT) or L ‐arginine (Arg) on fat absorbability, serum free fatty acid profiles and intestinal morphology in rats with short‐bowel syndrome (SBS) were studied using gas chromatography. Twenty‐eight Sprague‐Dawley rats were randomly assigned to 4 groups:sham operation fed with LCT as control; 85% small bowel resection fed with LCT, MCT/LCT, and Arg/LCT, respectively. SBS rats showed a decrease of fat absorptivity. Enteral nutrition supplemented with MCT could increase fat absorptivity. L ‐Arginine enhanced enteral nutrition was associated with the elevation of fat absorptivity, possibly due to its enterotrophic effect on remnant small bowel mucosa. LCT group showed a significant deficiency of total free fatty acid and the decreased essential fatty acid content, which was improved in other two SBS groups.