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Study of the Interaction of Cephalosporin Class Medicine with Albumin by Fluorescence Enhancement and Fluorescence Quenching Theories
Author(s) -
Yang ManMan,
Xiao Qin,
Xi XiaoLi
Publication year - 2006
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.200690123
Subject(s) - chemistry , quenching (fluorescence) , fluorescence , dissociation constant , photochemistry , binding constant , analytical chemistry (journal) , chromatography , binding site , biochemistry , physics , receptor , quantum mechanics
The interaction of 7 kinds of cephalosporin‐medicine with HSA and BSA was studied and compared using fluorescence enhancement and fluorescence quenching method, then deeply analyzed. The binding characteristics of medicine with albumin and usual characteristic constants such as dissociation constant, quenching constant, quenching efficiency, energy‐transfer efficiency and the distance between donor and accepter were also deeply analyzed.