Premium
Synthesis of Novel Nucleoside Analogues Based on 1,3‐Dihydrobenzo[ c ]furan Core
Author(s) -
Liu ZhaoPeng,
Meng ZhaoLi,
Wang DeFeng
Publication year - 2006
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.200690097
Subject(s) - chemistry , furan , guanosine , uracil , nucleoside , stereochemistry , combinatorial chemistry , organic chemistry , dna , biochemistry
A novel efficient synthetic route to 1,3‐dihydrobenzo[ c ]furan glycone was developed and the corresponding 5‐fluoro, 5‐iodo uracil and guanosine derivatives, the aromatic analogues of the well known antiviral 2′,3′‐dideoxy‐2′,3′‐dihydronucleosides (d4N), were synthesized.