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Electrochemical and Spectroscopic Studies on the Interaction between Tetracoordinate Macrocyclic Copper(II), Nickel(II) and Cobalt(III) Complexes with DNA
Author(s) -
Zhang ShuSheng,
Niu ShuYan,
Jie GuiFen,
Li XueMei,
Qu Bin
Publication year - 2006
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.200690049
Subject(s) - tetracoordinate , chemistry , nickel , cobalt , cyclic voltammetry , copper , electrochemistry , crystallography , dna , inorganic chemistry , stereochemistry , organic chemistry , biochemistry , computer graphics (images) , electrode , computer science , planar
Mononuclear copper(II), nickel(II) and cobalt(III) tetracoordinate macrocyclic complexes were synthesized and spectroscopically characterized. The crystal structure of the three compounds were determined by X‐ray crystallography. The electrochemical experimental results indicate that the three complexes could interact with DNA mainly by electrostatic interaction. The interaction of tetracoordinate macrocyclic cobalt(III) complex with DNA was studied by cyclic voltammetry and UV‐vis spectroscopy. The experimental results reveal that tetracoordinate macrocyclic cobalt(III) complex could interact with DNA by electrostatic interaction to form a 1:1 DNA association complex with a binding constant of 7.50×10 3 L·mol −1 .