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Reduction and Coupling Reaction of Carbonyl Compounds by Aluminum Powder and a Small Amount of Oxalic Acid in Water
Author(s) -
Yuan ShiZhen,
Wang ZhiYong,
Li Zhen
Publication year - 2006
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.200690011
Subject(s) - chemistry , oxalic acid , pinacol , aryl , aluminium , coupling (piping) , organic chemistry , catalysis , metallurgy , alkyl , materials science
Abstract A convenient pinacol coupling of aromatic aldehydes and aryl methyl ketones has been achieved with high yields by aluminum powder in the presence of oxalic acid in water. However, the diastereoselectivities of pinacols were not satisfying, and most aliphatic aldehydes and diaryl ketones have been found to be unreactive under the same conditions.