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Facile and Efficient Asymmetric Synthesis of α ‐Aminoalkylphosphonic Acids
Author(s) -
Yuan ChengYe,
Chen QianYi
Publication year - 2005
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.200591671
Subject(s) - chemistry , enantiomer , combinatorial chemistry , enantioselective synthesis , enantiomeric excess , chiral auxiliary , chemical synthesis , organic chemistry , catalysis , biochemistry , in vitro
An improved procedure for the asymmetric synthesis of α ‐aminoalkylphosphonic acids using S ‐2‐anilino‐methylpyrrolidine as the chiral auxiliary was described. The chemical transformations involved in this protocol could proceed under mild reaction condition to provide good chemical and enantiomeric yields.