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Conversion of N ‐Acyl‐4‐phenyl/benzyl‐oxazolidine‐2‐thiones into Thiol Esters in the Presence of EtSH‐K 2 CO 3
Author(s) -
Hu Qi,
Sun YaPing,
Wu YiKang
Publication year - 2005
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.200591561
Subject(s) - chemistry , thiol , oxazolidine , medicinal chemistry , catalysis , organic chemistry , stereochemistry
N ‐Acyl‐ β ‐hydroxy‐4‐phenyl‐oxazolidinethiones could be rapidly converted into their ethyl thiol esters in high yields by treatment with EtSH at 0 °C in CH 3 CN or 9:1 ( V : V ) THF‐H 2 O in the presence of a catalytic amount of K 2 CO 3 .
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