Seven New Sesquiterpene Lactones from Eupatorium chinense

Seven new sesquiterpenoids, namely eupatochinilides I–VII ( 1 – 7 ), together with eight known compounds, euponin ( 8 ), mollisorin A ( 9 ), niveusin B ( 10 ), 8 β ‐(4′,‐acetoxy‐tiglyloxy)‐3 β ‐hydroxy‐6 H β ,7 H α ‐germacra‐1(10) E ,4 E ,11(13)‐trien‐6,12‐olide ( 11 ), eupalinilide B ( 12 ), 8 β ‐(4′‐hydroxytigloyloxy)‐5‐desoxy‐8‐desacyleuparotin ( 13 ), 3‐deacetyeupalinin A ( 14 ), and 15‐hydroxyleptocarpin ( 15 ), were isolated from the ethanolic extract of the whole plant of Eupatorium chinense L. Their structures and stereochemistry were established by spectroscopic methods and GIAO based 13 C NMR chemical shift calculations.