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Synthesis and in vitro Antimalarial Activity of Several Simple Analogues of Peroxyplakoric Acid
Author(s) -
Liu HeHua,
Jin HongXia,
Zhang Qi,
Wu YiKang,
Kim HyeSook,
Wataya Yusuke
Publication year - 2005
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.200591469
Subject(s) - chemistry , in vitro , combinatorial chemistry , scope (computer science) , simple (philosophy) , stereochemistry , biochemistry , philosophy , epistemology , computer science , programming language
Several simple analogues of peroxyplakoric acid were synthesized by using Kobayashi's method to construct the key 1,2‐dioxane core and tested in vitro for antimalarial activity. The scope and limitation of the method was also briefly examined.