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Synthesis, Characterization and the Biological Activity of a Polyoxometalate‐loaded Nanosize‐liposome Complex
Author(s) -
Yang Yong,
Wang XiaoHong,
Xü Hong,
Chen Xin,
Liang GuoMing,
Gou Jin,
Li Bin,
Liu JingFu,
Du XiaoWang
Publication year - 2005
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.200591397
Subject(s) - polyoxometalate , chemistry , liposome , elemental analysis , nuclear chemistry , particle size , crystallography , inorganic chemistry , organic chemistry , catalysis , biochemistry
The polyoxometalate K 6 H[CoW 11 O 39 (CpTi)] (abbreviated as CoW 11 CpTi, Cp= η 5 ‐C 5 H 5 ) loaded nanosize‐liposome complex has been prepared and structurally characterized by elemental analysis, IR and UV spectra. The particle size of the complex was distributed in the range of 100–250 nm with the average diameter of 132.6 nm. The result showed that the polyoxometalate retained the parent structure after being encapsulated by liposome and liposomal encapsulation increased the antitumoral activity of the polyoxometalate.