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Facile Synthesis and Characterization of Bioactive N ‐[(1‐Ferrocenylethylidene)amino]‐ N ′ ‐ β ‐ D ‐glycopyranosylthiourea
Author(s) -
Zhang ShuSheng,
Yang Bo,
Li HuiXiang,
Jiao Kui
Publication year - 2005
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.200591253
Subject(s) - chemistry , monosaccharide , xylose , characterization (materials science) , stereochemistry , elemental analysis , galactose , combinatorial chemistry , organic chemistry , nanotechnology , fermentation , materials science
Several novel N ‐[(1‐ferrocenylethylidene)amino]‐ N ′ ‐ β ‐ D ‐glycopyranosylthioureas have been efficiently synthesized via a six‐step procedure, utilizing three monosaccharides ( D ‐glucose, D ‐galactose and D ‐xylose) as starting materials, respectively. They have been preliminarily determined to display biological activity against certain fungi. The target compounds have been unambiguously characterized by spectroscopic method and elemental analysis. An initially alternative synthetic route, which was seemingly reasonable, has been excluded due to its inefficiency.