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One‐pot Synthesis of N ‐Hydroxylacridine Derivatives in Water
Author(s) -
Shi DaQing,
Mou Jie,
Zhuang QiYa,
Wang XiangShan
Publication year - 2005
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.200591223
Subject(s) - chemistry , hydroxylamine hydrochloride , hydrochloride , catalysis , hydroxylamine , chloride , organic chemistry , reaction conditions , component (thermodynamics) , yield (engineering) , combinatorial chemistry , physics , thermodynamics , materials science , metallurgy
N ‐Hydroxylacridinedione derivatives were synthesized by three‐component reaction of aromatic aldehydes, 1,3‐dicarbonyl compounds and hydroxylamine hydrochloride using triethylbenzylammonium chloride (TEBA) as the catalysis in water. The reaction has many advantages including good yields, easy to be separated and environmental friendliness.