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Directional Self‐assembly in Archaerhodopsin‐Reconstituted Phospholipid Liposomes
Author(s) -
Jia Wu,
Li Huang,
Jian Liu,
Ming Ming,
QingGuo Li,
JianDong Ding
Publication year - 2005
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.200590330
Subject(s) - chemistry , liposome , phospholipid , self assembly , nanotechnology , biophysics , combinatorial chemistry , biochemistry , organic chemistry , membrane , biology , materials science
This paper reports, for the first time, that Archaerhodopsin‐4 (AR4) could be reconstituted into phospholipid liposomes by self‐assembly. AR4 is a new membrane protein isolated from halobacteria H. sp . xz515 in a salt lake of Tibet, China. This is a bacteriorhodopsin (bR) like protein, function as a light‐driven proton pump. Experimental measurements verified that similar to bR, AR not only remains its biological activity in proteoliposome, but also keeps a preferred orientation in self‐assembly.