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Reaction of ketene dithioacetals with pyrazolylcarbohydrazide: Synthesis and biological activities of ethyl 5‐amino‐1–(5′‐methyl‐1′‐ t ‐butyl‐4′‐pyrazolyl)carbonyl‐3‐methylthio‐1 H ‐pyrazole‐4‐carboxylate
Author(s) -
Li Ming,
Wen LiRong,
Fu WeiJun,
Zhao GuiLong,
Hu FangZhong,
Yang HuaZheng
Publication year - 2004
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.20040220936
Subject(s) - chemistry , ketene , pyrazole , ethanol , medicinal chemistry , carboxylate , organic chemistry
The title compound, C 16 H 23 N 5 O 3 S, ethyl 5‐amino‐l‐(5′‐methyl‐l'‐ t ‐butyl‐4′‐pyrazolyl)carbonyl‐3‐methylthio 1 H ‐pyrazole‐4‐carboxylate (5) has been synthesized by the treatment of ethyl 2‐cyano‐3,3‐dimethylthioacrylate with 1 ‐ t ‐butyl‐5‐methyl‐4‐hydrazinocarbonylpyrazole (4) in refluxed ethanol. The possible mechanism of the above reaction was also discussed. The results of biological test show that the title compound has fungicidal and plant growth regulation activities.