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CuCl/Zn‐promoted Mukaiyama aldol reaction of phenyl α‐fluoro silyl enol ether with aldehydes
Author(s) -
Zhou DingYing,
Chen UmgYun
Publication year - 2004
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.20040220916
Subject(s) - chemistry , aldol reaction , silylation , enol , silyl enol ether , enol ether , organic chemistry , silyl ether , medicinal chemistry , catalysis
2‐Fluoro‐1‐phenyl‐1‐trimethylsiloxyethene reacted efficiently with aldehydes to give α‐fluoro β ‐hydroxy ke‐tones in HMPA in the presence of Zn powder and CuCl.