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Ring‐closure reaction to novel quinoline derivatives and their structural characterization
Author(s) -
Lu YinXiang,
Lan BiJian,
Zhou Hui,
Xu Wei,
Wang JingMei,
Huang YongMing
Publication year - 2004
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.20040220818
Subject(s) - chemistry , quinoline , ring (chemistry) , substituent , closure (psychology) , condensation , crystal structure , product (mathematics) , condensation reaction , stereochemistry , medicinal chemistry , crystallography , organic chemistry , catalysis , physics , geometry , mathematics , economics , market economy , thermodynamics
In the condensation of arylaldehydes with arylethylidenemalononitriles, it was found that, besides the normal product dienes a, the ring‐closure product quinoline derivatives b can be also obtained in 26%–50% yields. The substituent effects were also examined and a possible reaction mechanism was proposed for the formation of b. The X‐ray crystal structure of 1b confirms the structure of the ring‐closure product.