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Synthesis, characterization and the effect of glucose‐lowering of guanidino acid oxovanadium(IV) complexes
Author(s) -
Liu JuTao,
Wang XiaoHong,
Li JianXin,
Liu JingFu
Publication year - 2004
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.20040220729
Subject(s) - chemistry , propanoic acid , in vivo , acetic acid , stereochemistry , medicinal chemistry , biochemistry , microbiology and biotechnology , biology
Two guanidino acid oxovanadium(IV) complexes have been synthesized. Preliminary tests in vivo have shown that the two title complexes all display lowering glucose activity in vivo to STZ‐rats. The effect of glucose‐lowering of guanidino acetic acid oxovanadium(IV) complex in vivo is higher than that of guanidino propanoic acid oxovanadium(IV) complex.