Premium
Synthesis of (ρ‐formylphenyl)azo calix[4]arenes
Author(s) -
Bal Zhu,
Yu Lei,
Lu GuoYuan,
Guo Xun
Publication year - 2004
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.20040220521
Subject(s) - chemistry , molar ratio , calixarene , diazo , aqueous solution , proton nmr , hydrochloride , sodium nitrite , medicinal chemistry , organic chemistry , catalysis , molecule
Five novel azo calix[4]arenes were reported. The p ‐aminobenzaldehyde was diazotized with sodium nitrite in aqueous hydrochloride solution. Mono‐, bis‐, his‐ and tetrakis( p ‐formylphenyl)azo calix[4]arenes (including proximal and distal isomers) were obtained respectively by diazo‐coupling in different molar ratio to calix[4]arene (1) under pH=7.5‐8.5 at 0‐5 C. All ( p ‐formylphenyl)azo calix[4]arenes were characterized by 'H NMR, 13 C NMR, IR, MS (ESIMS) spectroscopies and elemental analysis.