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Synthesis, Structure and Biological Activity of Zn(ll) Complex with Tris(benzimidazol‐2‐yl‐methyl)amine Ligand
Author(s) -
Liu XiaoLan,
Zhao Ru,
Liu XiaoHong,
Yue JunJie,
Yin YuXin,
Sun Yun,
Sun Ming
Publication year - 2004
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.20040220117
Subject(s) - chemistry , ligand (biochemistry) , crystal structure , crystallography , amine gas treating , imidazole , tris , zinc , pyrogallol , stereochemistry , organic chemistry , biochemistry , receptor
A new Zn(II) mononuclear complex with tris(benzimidazol‐2‐yl‐methyl)amine (NTB) was synthesized with stoichiometry of [Zn(NTB)NO 3 ]NO 3 · DIPY · DMF (DIPY : 4,4′‐dipyridyl). The complex was characterized by elemental analysis, UV and IR spectra. The crystal structure was determined by using X‐ray diffraction analysis. The crystal structure indicates that four N atoms and one O atom coordinate to zinc ion to construct a distorted trigonal‐dipyramid configuration. Three nonprotonated N atoms from imidazole groups are in the equatorial plane, one alkylamino N atom and one O atom from NO 3 − ‐ in the axial directions. The biological activity assay shows that this complex presents certain biological activity by means of pyrogallol autoxidation and it can be called a model compound of superoxide dismutase (SOD).