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Fabrication of Dendrimer‐like PAMAM Based on Silica Nanoparticles
Author(s) -
Liu Peng,
Tian Jun,
Liu WeiMin,
Xue QunJi
Publication year - 2003
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.20030210747
Subject(s) - dendrimer , chemistry , nanoparticle , fourth generation , amine gas treating , methanol , acrylate , grafting , chemical engineering , polymer chemistry , fabrication , nanotechnology , organic chemistry , third generation , copolymer , polymer , materials science , telecommunications , computer science , engineering , medicine , alternative medicine , pathology
A G 4.0 dendrimer‐like poly(amido amine) (PAMAM) based on silica nanoparticles was fabricated via a divergent approach. It was built from γ‐aminopropyl silica nanoparticles (APSN) core via repetitive addition of acrylate (MA) and hexylenediamine (HDA). FT‐IR and EA were used to monitor the progress of dendrimer during each step. The amino group content of the resulting product increased from 0.49 to 3.72 mmol/g after the 4th generation. In addition, the percentage of grafting increased with increasing generation and reached to 65.9% after 4th generation. It was found that the resulting silica nanoparticles could be dispersed in methanol with a mean hydrodynamic particle diameter of 152.7 nm although the silica nanoparticles had agglomerated during the storage period.