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Alkylation of Sulfur Ligand in Cysteinate‐Iron Chelates by a 1,2,4, 5‐Tetraoxane
Author(s) -
Liu HeHua,
Wu YiKang,
Shen Xin
Publication year - 2003
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.20030210731
Subject(s) - chemistry , yield (engineering) , chelation , organic chemistry , metallurgy , materials science
Reaction of a 1, 2, 4, 5‐tetraoxane with cysteinate‐iron in the presence of excess methyl cysteinate led to formation of sulfuralkylated methyl cysteinate in 33% yield, illustrating a possible mechanism for tetraoxanes'antimalarial action.