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Microspheres Sensor Based on Molecularly Imprinted Polymer Synthesized by Precipitation Polymerization
Author(s) -
ZhaoHui Zhang,
YuMei Long,
YingJu Liu,
ShouZhuo Yao
Publication year - 2003
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.20030210515
Subject(s) - chemistry , molecularly imprinted polymer , precipitation polymerization , detection limit , polymerization , dissociation constant , dissociation (chemistry) , precipitation , polymer , analytical chemistry (journal) , chromatography , radical polymerization , selectivity , organic chemistry , catalysis , biochemistry , receptor , physics , meteorology
A new biomimetic bulk acoustic wave sensor based on molecularly imprinted microspheres (MIM) technique was described. The sensing materials were synthesized by precipitation polymerization. By using the Scatchard analysis, the equilibrium dissociation constant K D and the apparent maximum number Q max of the binding sites were calculated to be 3.70 mmol·L −1 and 9.11 μmol·g −1 , respectively. The sensor exhibited a sensitive response to the template compound (dipyridamole) in liquid phase with a detection limit of 2 × 10– 9 mol· L −1 . The recoveries of the sensor were 95.1%‐105.4%. Studies presented in this paper show that the stability of this sensor is excellent. The sensor has been applied successfully to the determination of dipyridamole in human urine.