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A Short and Highly Stereoselective Synthesis of Cerebrosterol
Author(s) -
Zhang DongHiri,
Zhou XiangDong,
Zhou WeiShan
Publication year - 2002
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.20020201104
Subject(s) - chemistry , stereoselectivity , yield (engineering) , key (lock) , combinatorial chemistry , stereochemistry , organic chemistry , catalysis , ecology , materials science , metallurgy , biology
The title compound, cerebrosterol, has been synthesized in five steps with 61.5% overall yield and > 99.9% de from 3α, 6α ‐dimethoxymethoxyl‐5P‐cholane‐24‐al as a key intermediate, which was prepared from methyl 3α , 6α‐dihydroxy hyodeoxy‐cholanate.
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