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Novel asymmetric total synthesis of (+)‐6‐epicastanospermine
Author(s) -
Zhang HongXing,
Xia Peng,
Zhou WeiShan
Publication year - 2001
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.20010191225
Subject(s) - chemistry , total synthesis , yield (engineering) , acrylate , derivative (finance) , enantioselective synthesis , stereochemistry , combinatorial chemistry , organic chemistry , monomer , catalysis , polymer , metallurgy , materials science , economics , financial economics
Abstract An asymmetric total synthesis of (+)‐6‐epicastanospermine was achieved in 13 steps and 19% overall yield from β‐hydroxy‐α‐furfurylamine derivative, which was prepared by Sharpless asymmetric aminohydroxylation of furyl acrylate.