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Palladium(II)‐catalyzed cyclization of W‐(2′,4′‐dienyl)‐2‐alkynamides to α‐alkylidene‐γ‐butyrolactams
Author(s) -
He Xa,
Lu HYan,
Liu GuoSheng
Publication year - 2001
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.20010191221
Subject(s) - chemistry , palladium , catalysis , cleavage (geology) , medicinal chemistry , oxidative cleavage , bond cleavage , organic chemistry , geotechnical engineering , fracture (geology) , engineering
In the presence of CuCl 2 , N‐ (2′, 4′‐dienyl)‐2‐alkynamides can be converted to α‐alkylidene‐σ‐butyrolactams under the catalysis of palladium(II). In this reaction, CuCl 2 is used to oxidize Pd(0) to regenerate Pd(II), or the carbon‐palladium bond is quenched by the oxidative cleavage reaction of CuCl 2 .
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