Premium
A new and facile synthesis of 6‐methyl‐2‐trifluoromethyl‐4‐( O,O ‐ dialkyl) phosphoryl‐ quinoline
Author(s) -
Gong DengHuang,
Li JinFeng,
Yuan ChengYe
Publication year - 2001
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.20010191217
Subject(s) - chemistry , quinoline , trifluoromethyl , medicinal chemistry , combinatorial chemistry , organic chemistry , alkyl
Palladium‐catalyzed coupling reaction of trifluoromethylacetimidoyl iodide with dialkyl vinylphosphonates afforded trifluoromethylated and phosphorylated α, β‐unsatured imines, which gave corresponding quinoline derivatives upon cyclization with Pd/C in nitrobenzene.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom