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Solid‐state Asymmetric Reduction of ( S )‐1, 1′‐Bi‐2‐naphthol‐Acetylferrocene Molecular Compound with Sodium Borohydride
Author(s) -
Du HaiFeng,
Ding KuiLing,
Meng JiBen
Publication year - 2001
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.20010190717
Subject(s) - chemistry , enantiopure drug , sodium borohydride , borohydride , asymmetric induction , reduction (mathematics) , solid state , sodium , crystal (programming language) , combinatorial chemistry , organic chemistry , enantioselective synthesis , catalysis , geometry , mathematics , computer science , programming language
A novel molecular crystal formed between enantiopure 1,1′‐bi‐2‐naphthol and acetylferrocene has been prepared and characterized in this communication. The examination on its reduction with sodium borohydride showed that the asymmetric induction was observed in the solid state but not in the solution phase. The asymmetric induction in the solid‐state reduction may be attributed to the chiral microenvironment of molecular crystal.