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Chiral Camphor Derivatives as New Catalysts for Asymmetric Phase‐Transfer Alkylation
Author(s) -
Zhang Jie,
Wu XinYan,
Zhou QiLin,
Sun Jie
Publication year - 2001
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.20010190617
Subject(s) - chemistry , alkylation , benzophenone , camphor , catalysis , bromide , phase (matter) , benzyl bromide , organic chemistry , imine , enantioselective synthesis , combinatorial chemistry
The synthesis of new chiral phase‐transfer catalysts based on the optical camphor is described. The alkylation of the benzophenone imine of glycine tert‐butyl ester with benzyl bromide in the presence of new chiral phase‐transfer catalysts afforded the desired alkylation product in good yields and up to 39% ee .