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1,3‐Dipolar Cycloaddition of Nitrones with Electron‐rich Alkenes Catalyzed by Yb(OTf) 3
Author(s) -
Qian ChangTao,
Wang LongCheng,
Chen RuiFang
Publication year - 2001
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.20010190417
Subject(s) - chemistry , cycloaddition , catalysis , trifluoromethanesulfonate , stereoselectivity , 1,3 dipolar cycloaddition , nitrone , organic chemistry , ytterbium , medicinal chemistry , combinatorial chemistry , physics , optoelectronics , doping
1,3‐Dipolar cycloaddition of nitrones with ethyl vinyl ether or 2,3‐dihydrofuran proceeds smoothly in the presence of a catalytic amount (10 mol%) of ytterbium triflate to afford isoxazolidines and dicyclic isoxazolidine respectively with good yields and high stereoselectivity.